Description
Pantanu-L is a combination formulation containing pantoprazole sodium 40 mg and sustained-release (SR) levosulpiride 75 mg. It combines gastric acid suppression with prokinetic activity and may be prescribed for selected gastrointestinal conditions when both ingredients are considered appropriate.
Pantoprazole helps reduce stomach acid production, while levosulpiride may support upper gastrointestinal motility and help manage certain digestive symptoms. Since levosulpiride can cause neurological and hormonal adverse effects, treatment requires appropriate medical supervision.
Therapeutic Segment
Gastrointestinal Care | Acid Reflux Management | Prokinetic Therapy
Uses of Pantanu-L
A healthcare professional may prescribe Pantanu-L for selected gastrointestinal conditions where acid suppression and prokinetic treatment are both appropriate, such as:
- Gastroesophageal reflux symptoms.
- Selected functional dyspepsia symptoms, including post-meal fullness or upper abdominal discomfort.
- Certain upper gastrointestinal complaints associated with impaired motility, following clinical assessment.
The exact indication depends on the patient’s diagnosis and the approved product information.
Key Benefits
- Acid suppression: Pantoprazole reduces gastric acid secretion.
- Motility support: Levosulpiride may help improve upper gastrointestinal motility.
- Combination formulation: Combines a proton pump inhibitor with a prokinetic agent.
- Symptom-focused treatment: May be considered when a clinician determines that both ingredients are necessary.
Response varies between patients. This product should not be presented as a guaranteed cure or as suitable for every digestive complaint.
How Pantanu-L Works
Pantoprazole sodium 40 mg belongs to the proton pump inhibitor (PPI) class. It inhibits the gastric proton pumps responsible for acid secretion, helping reduce stomach acidity.
Levosulpiride SR 75 mg is a substituted benzamide with dopamine D2 receptor-blocking activity. At appropriate doses, it can exert prokinetic effects and support upper gastrointestinal movement. However, dopamine blockade may also cause movement-related adverse effects and increased prolactin levels.
The sustained-release formulation is designed to release levosulpiride over an extended period. Follow the approved product label for exact release characteristics and administration instructions.
Possible Side Effects
Possible side effects may include:
- Headache
- Dizziness or drowsiness
- Abdominal discomfort
- Diarrhoea or constipation
- Restlessness or movement-related symptoms
Levosulpiride may also increase prolactin levels, potentially causing breast tenderness, unexpected breast milk production, menstrual irregularities or sexual dysfunction. Longer use may increase the risk of certain movement disorders.
Seek medical advice if side effects persist or worsen. Obtain prompt medical attention for severe muscle stiffness, abnormal involuntary movements, fainting or other serious symptoms.
Important Safety Information
- Use Pantanu-L only under the supervision of a qualified healthcare professional.
- Tell your prescriber about all medicines, supplements, allergies and existing medical conditions.
- Levosulpiride may not be suitable for people with certain movement disorders, epilepsy, prolactin-dependent conditions or gastrointestinal obstruction, bleeding or perforation.
- Inform your healthcare professional about kidney problems, as levosulpiride may require additional consideration in these patients.
- Discuss pregnancy or breastfeeding before using this medicine.
- Levosulpiride may cause drowsiness or dizziness. Avoid driving or operating machinery if affected.
- Do not stop, extend or change treatment without professional advice, especially if you have been taking it regularly.
- Seek medical evaluation for persistent symptoms, difficulty swallowing, unexplained weight loss, vomiting blood or black stools.
Dosage and Administration
Take Pantanu-L only as directed by your healthcare professional and according to the approved product label. The appropriate dose, timing and duration depend on the patient’s diagnosis, medical history and response to treatment.
Because the formulation contains sustained-release levosulpiride, follow the specific administration instructions. Do not crush, chew or open the dosage form unless the approved product instructions explicitly permit it.
Storage Instructions
Store Pantanu-L according to the conditions stated on the approved packaging. Keep it in its original Alu-Alu pack, protected from excessive heat and moisture, and out of reach of children. Confirm the exact storage requirements from the product label.






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