Omxol-D

Description

Omxol-D is a combination formulation containing Omeprazole 20 mg and Domperidone 10 mg, intended for use in selected acid-related gastrointestinal conditions when a healthcare professional considers both ingredients appropriate. Omeprazole reduces stomach acid production, while domperidone helps support stomach movement and may relieve certain symptoms such as nausea and vomiting.

The combination should be used only under medical supervision, as domperidone can increase the risk of serious heart rhythm problems in some patients.

Therapeutic Segment

Gastrointestinal Care | Acid Reflux Management | Prescription Digestive Care

Uses of Omxol-D

A healthcare professional may prescribe Omxol-D for selected conditions involving excess stomach acid and associated gastrointestinal symptoms, such as:

• Gastroesophageal reflux disease (GERD), when both ingredients are appropriate.
• Acid reflux associated with nausea or other relevant symptoms.
• Certain acid-related digestive complaints where a clinician recommends combination therapy.

The exact indication depends on the patient’s condition and the approved product label.

Key Benefits

• Acid reduction: Omeprazole helps reduce stomach acid production.
• Gastrointestinal symptom support: Domperidone may help relieve nausea and vomiting in appropriately selected patients.
• Combination formulation: Brings together two different mechanisms of action in one product.
• Prescription-based treatment: Allows a healthcare professional to assess whether both ingredients are necessary.

How Omxol-D Works

Omeprazole 20 mg belongs to the proton pump inhibitor (PPI) class. It reduces acid secretion in the stomach by inhibiting the acid-producing proton pumps.

Domperidone 10 mg is a dopamine receptor antagonist with prokinetic and antiemetic effects. It can help improve upper gastrointestinal motility and relieve nausea. However, it may prolong the QT interval and increase the risk of serious cardiac arrhythmias, particularly in susceptible patients or when interacting medicines are used.

Possible Side Effects

Possible side effects may include:

• Headache
• Abdominal discomfort or pain
• Diarrhoea or constipation
• Nausea
• Dry mouth

Important: Domperidone has been associated with serious heart rhythm disturbances. Seek urgent medical attention for fainting, a rapid or irregular heartbeat, or severe dizziness. Prolonged use of omeprazole may also carry risks that depend on treatment duration and individual health factors.

Important Safety Information

• Use Omxol-D only on the advice of a qualified healthcare professional.
• Domperidone may not be suitable for people with certain heart conditions, prolonged QT interval, significant electrolyte disturbances, or moderate to severe liver impairment.
• Tell your prescriber about all medicines you take, especially medicines that can prolong the QT interval or strongly inhibit CYP3A4.
• Do not use domperidone with medicines that may create clinically significant interactions. Your prescriber or pharmacist should review your medication list.
• Omeprazole can interact with some medicines, including clopidogrel; inform your healthcare professional if you take it.
• Do not exceed the prescribed dose or duration.
• Seek medical advice for persistent symptoms, difficulty swallowing, unexplained weight loss, vomiting blood, or black stools.

Dosage and Administration

Take Omxol-D only as prescribed and follow the instructions on the approved product label. The appropriate dose, timing and treatment duration depend on the patient’s diagnosis, age, medical history and other medicines.

Do not increase the dose or continue treatment longer than advised. Because domperidone carries cardiac risks, the prescriber should confirm that it is necessary and appropriate for you.

Storage Instructions

Store the product according to the approved packaging instructions. Keep it in its original pack, away from excessive heat and moisture, and out of reach of children. Confirm the specific storage conditions from the product label.