Rabizn-DSR

Description

Rabizn-DSR combines Rabeprazole 20 mg with Domperidone 30 mg in a sustained-release formulation. These ingredients act through different mechanisms to help manage certain acid-related digestive conditions when prescribed by a healthcare professional.

Rabeprazole reduces stomach acid production, while Domperidone supports gastrointestinal motility and may help relieve associated nausea in appropriate patients. Therefore, this combination may be prescribed for selected cases involving acid reflux and related digestive symptoms. Its suitability depends on the patient’s symptoms, medical history and the prescriber’s assessment.

Therapeutic Segment

Gastroenterology | Acid Reflux Management | Peptic Ulcer-Related Conditions

Uses of Rabizn-DSR

A healthcare professional may prescribe Rabizn-DSR for selected acid-related digestive conditions, including:

• Gastroesophageal reflux disease (GERD), when this combination is appropriate.
• Acid reflux associated with heartburn or regurgitation.
• Certain conditions involving excessive stomach acid and associated digestive symptoms.
• Acid-related discomfort accompanied by nausea, when the prescriber considers both ingredients necessary.

Important: This medicine is not suitable for every case of acidity, nausea or indigestion. Domperidone has important cardiac safety considerations, so treatment should follow medical advice.

Key Benefits

• Helps reduce stomach acid: Rabeprazole decreases acid secretion in the stomach.
• Supports reflux management: Reduced acid production may help relieve acid-related symptoms.
• Supports gastrointestinal motility: Domperidone can help improve stomach emptying in selected patients.
• Combines two active ingredients: The formulation addresses acid secretion and selected motility-related symptoms through different mechanisms.
• Sustained-release formulation: Domperidone is listed as sustained release in the supplied composition; confirm the exact dosage form and release characteristics from the approved product label.

Individual results vary. This medicine does not guarantee symptom relief and should be used only when prescribed.

How Rabizn-DSR Works

Rabizn-DSR contains two active ingredients:

Rabeprazole 20 mg: Rabeprazole belongs to the proton pump inhibitor (PPI) class. It reduces the amount of acid produced by the stomach by inhibiting the gastric proton pump.

Domperidone 30 mg Sustained Release: Domperidone acts mainly on dopamine receptors and can promote gastrointestinal motility. It may also help control nausea in appropriate circumstances. Its use requires particular care because it can increase the risk of serious heart rhythm problems in some patients.

Together, the ingredients may help manage selected acid-related conditions when a clinician determines that the combination is appropriate.

Possible Side Effects

Some people may experience side effects while taking Rabizn-DSR, including:

• Headache
• Abdominal discomfort or stomach pain
• Diarrhoea or constipation
• Nausea
• Dry mouth
• Dizziness

Seek urgent medical attention if you experience a fast or irregular heartbeat, fainting, severe dizziness, facial or throat swelling, or difficulty breathing. Domperidone can cause serious heart rhythm disturbances, particularly in people with certain heart conditions, electrolyte abnormalities or interacting medicines.

Contact your healthcare professional if side effects persist or become troublesome.

Important Safety Information

• Use Rabizn-DSR only under the supervision of a qualified healthcare professional.
• Domperidone may increase the risk of QT prolongation and serious ventricular arrhythmias. The prescriber should assess cardiac risk before recommending treatment.
• Tell your doctor if you have heart disease, a history of abnormal heart rhythms, liver problems or low potassium or magnesium levels.
• Inform your doctor about all medicines you take, particularly medicines that prolong the QT interval or strongly inhibit CYP3A4, including certain antibiotics and antifungal medicines.
• Tell your healthcare professional if you are pregnant, planning pregnancy or breastfeeding.
• Long-term use of rabeprazole may require medical review because prolonged proton pump inhibitor treatment can be associated with certain nutrient deficiencies, low magnesium and other risks.
• Do not use this medicine to self-treat recurring symptoms without identifying their cause.
• Seek medical advice promptly for difficulty swallowing, unexplained weight loss, persistent vomiting, vomiting blood or black stools.

Dosage and Administration

Take Rabizn-DSR exactly as prescribed by your healthcare professional. The appropriate dose and duration depend on the diagnosis, individual risk factors and the approved formulation.

• Follow the prescribed timing and instructions on the product label.
• Do not crush, chew or open a sustained-release dosage form unless the approved product instructions specifically permit it.
• Do not increase the dose or extend treatment on your own.
• If you miss a dose, follow your prescriber’s instructions or the patient leaflet. Do not take an extra dose to compensate.

Because Domperidone carries important cardiac risks, use the lowest effective dose for the shortest duration considered appropriate by the prescriber.

Storage Instructions

• Store according to the conditions printed on the approved product packaging.
• Keep the medicine in its original blister packaging until use.
• Protect it from excessive heat, moisture and direct sunlight.
• Keep it out of the reach of children.
• Do not use tablets or capsules after the expiry date or if the packaging is damaged.